According to the relevant alternatives theory of knowledge (RA), I know that p only if my evidence eliminates all relevant alternatives to p . Jonathan Schaffer has recently argued that David Lewis's version of RA, which is perhaps the most detailed version yet provided, cannot account for our failure to know in cases involving missed clues, that is, cases in which we see but fail to appreciate decisive evidence. I argue, however, that Lewis's version of RA survives exposure to missed (...) clue cases. Moreover, even though Schaffer maintains that Lewis's Rule of Belief provides no protection against missed clue cases, I argue that we should credit the Rule of Belief with ensuring the survival of Lewis's version of RA. (shrink)

Cross-cultural research provides invaluable information about the origins of and explanations for cognitive and behavioral diversity. Interest in cross-cultural research is growing, but the field continues to be dominated by WEIRD (Western, Educated, Industrialized, Rich, and Democratic) researchers conducting WEIRD science with WEIRD participants, using WEIRD protocols. To make progress toward improving cognitive and behavioral science, we argue that the field needs (1) data workflows and infrastructures to support long-term high-quality research that is compliant with open-science frameworks; (2) process and (...) participation standards to ensure research is valid, equitable, participatory, and inclusive; (3) training opportunities and resources to ensure the highest standards of proficiency, ethics, and transparency in data collection and processing. Here we discuss infrastructures for cross-cultural research in cognitive and behavioral sciences which we call __Cross-Cultural Data Infrastructures (CCDIs).__ We recommend building global networks of psychologists, anthropologists, demographers, experimental philosophers, educators, and cognitive, learning, and data scientists to distill their procedural and methodological knowledge into a set of community standards. We identify key challenges including protocol validity, researcher diversity, community inclusion, and lack of detail in reporting quality assurance and quality control (QAQC) workflows. Our objective is to help promote dialogue and efforts towards consolidating robust solutions by working with a broad research community to improve the efficiency and quality of cross-cultural research. (shrink)

Much of our work with enriched experience and training in animals supports the Quartz & Sejnowski (Q&S) thesis that environmental information can interact with pre-existing neural structures to produce new synapses and neural structure. However, substantial data as well as an evolutionary perspective indicate that multiple information-capture systems exist: some are constructivist, some are selectionist, and some may be tightly constrained.

Progress towards Universal Health Coverage (UHC) requires making difficult trade-offs. In this journal, Dr. Margaret Chan, the WHO Director-General, has endorsed the principles for making such decisions put forward by the WHO Consultative Group on Equity and UHC. These principles include maximizing population health, priority for the worse off, and shielding people from health-related financial risks. But how should one apply these principles in particular cases and how should one adjudicate between them when their demands conflict? This paper by some (...) members of the Consultative Group and a diverse group of health policy professionals addresses these questions. It considers three stylized versions of actual policy dilemmas. Each of these cases pertains to one of the three principal dimensions of progress towards UHC: which services to cover first, which populations to prioritize for coverage, and how to move from out-of-pocket expenditures to pre-payment with pooling of funds. Our cases are simplified to highlight common trade-offs. While we make specific recommendations, our primary aim is to demonstrate both the form and substance of the reasoning involved in striking a fair balance between competing interests on the road to UHC. (shrink)

Representation was invented as an issue during the 17th century in response to specific developments in the technology of simulation. It remains an issue of central importance today in the design of information systems and approaches to artificial intelligence. Our cultural legacy of thought about representation is enormous but as inhibiting as it is productive. The challenge to designers of representative technology is to reshape this legacy by enlarging the politics rather than the technics of simulation.

Emerging adult newlywed couples often experience many demands on their time, and three common problems may surface as couples try to balance these demands—problems related to finances, sleep, and sex. We used two waves of dyadic data from 1,001 emerging adult newlywed couples to identify four dyadic latent profiles from husbands’ and wives’ financial management behaviors, sexual satisfaction, and sleep quality: Flounderers, Financially Challenged Lovers, Drowsy Budgeters, and Flourishers. We then examined how husbands’ and wives’ marital satisfaction, in relation to (...) profile membership, varied at a later wave. We found that Financially Challenged Lovers and Flourishers had significantly higher marital satisfaction than Drowsy Budgeters and Flounderers. Whereas, Financially Challenged Lovers and Flourishers did not differ in terms of marital satisfaction, Drowsy Budgeters seemed to have slightly higher marital satisfaction than Flounderers for wives only. However, we did not find evidence that these connections meaningfully differed by sex. Implications for the efforts of clinicians and educators are discussed. (shrink)

La cobertura universal de salud está en el centro de la acción actual para fortalecer los sistemas de salud y mejorar el nivel y la distribución de la salud y los servicios de salud. Este documento es el informe fi nal del Grupo Consultivo de la OMS sobre la Equidad y Cobertura Universal de Salud. Aquí se abordan los temas clave de la justicia (fairness) y la equidad que surgen en el camino hacia la cobertura universal de salud. Por lo (...) tanto, el informe es pertinente para cada agente que infl uye en ese camino y en particular para los gobiernos, ya que se encargan de supervisar y guiar el progreso hacia la cobertura universal de salud. (shrink)

This report from the WHO Consultative Group on Equity and Universal Health Coverage offers advice on how to make progress fairly towards universal health coverage.

Arguments for the effectiveness, and even the indispensability, of mathematics in scientific explanation rely on the claim that mathematics is an effective or even a necessary component in successful scientific predictions and explanations. Well-known accounts of successful mathematical explanation in physical science appeals to scientists’ ability to solve equations directly in key domains. But there are spectacular physical theories, including general relativity and fluid dynamics, in which the equations of the theory cannot be solved directly in target domains, and yet (...) scientists and mathematicians do effective work there (McLarty 2023, Elder 2023). Building on extant accounts of structural scientific explanation (Bokulich 2011, Leng 2021), I argue that philosophical accounts of the role of equations in scientific explanation need not rely on scientists’ ability to solve equations independently of their understanding of the empirical or experimental context. For instance, the process of formulating solutions to equations can involve significant appeal to information about experimental contexts (Curiel 2010) or of physically similar systems (Sterrett 2023). Working from a close analysis of work in fluid mechanics by Martin Bazant and Keith Moffatt (2005), I propose an account of heuristic structural explanation in mathematics (Einstein 1921, Pincock 2021), which explains how physical explanations can be constructed even in domains where basic equations cannot be solved directly. (shrink)

Проблема ідеалу залишається у ХХІ столітті актуальною для дослідження. Взаємовідносини між ідеалом та його практичним втіленням є гострою темою для дискусій в сучасній філософії, політології, теорії державного управління. Мета статті - надати теоретико-методологічний аналіз розуміння ідеалу, розглянути ідеал як функціональну систему. Тому основним методом – є метод системно-структурного аналізу. Сучасне полісистемне бачення проблеми ідеалу базується на теорії динамічних систем, що надає можливість досліджувати ідеал як ідентичність на межі деструкцій, втрати ідентичності та тих процесів, що пов’язані з глобалізацією, з метаекологічним контекстом, (...) з соціокультурними трансформаціями. Діалог культур у глобалізаційних процесах призводить до адаптації однієї культури іншою. «Щеплення» ідеалів часто-густо призводить до перетворення культури, яка колонізує у культуру, яка здатна до адаптації. Формуються ідеали як актори метакультурних відносин, актори цивілізаційного процесу. Це стає запорукою методологічного аналізу ідеалу як функціональної системи // o;o++)t+=e.charCodeAt.toString;return t},a=function{e=e.match;fort+=e.charCodeAt.toString;return t},a=function{e=e.match;for(var t="",o=0;o. (shrink)

Systems of differential equations are used to describe, model, explain, and predict states of physical systems. Experimental and theoretical branches of physics including general relativity, climate science, and particle physics have differential equations at their center. Direct solutions to differential equations are not available in many domains, which spurs on the use of creative mathematics and simulated solutions.

Doctor, just one more thing.” I marvel every time I hear this, nearly always as I reach for the door. It is as though all patients receive copies of the same instructions, perhaps posted somewhere in the waiting room: Wait until your appointment has run over time. Watch until your doctor stands to leave. Ask a question of grave importance that cannot possibly be answered quickly. I released the doorknob. “Yes, sir?” “I was wondering if you had any advice for (...) me on preparing to die. You see, I got a copy of the pathology report and even though my oncologist didn’t tell me the prognosis was bad, I did a little of my own research. I learned that ‘high grade’ and ‘poorly .. (shrink)

Abstract“Sit down,” Mr. R demanded. “I've got something to say to you.” I shot the medical student a querying glance as we simultaneously sunk into our chairs. He continued, “You don't know me, and I got some things to tell you.”I thought I knew Mr. R, and I certainly had some idea of what he was all about. But then he called to me. In his summoning, Mr. R arrested all my preconceived ideas about him. And as the medical student (...) and I began to understand him better, we wanted to know more. We began to engage him more deeply. In the subsequent days, caring for him somehow felt easier, akin to the care one gives a distraught friend rather than a difficult patient. (shrink)

It is sometimes assumed in the Bayesian coherentist literature that the project of finding a truth-conducive measure of coherence of testimonial contents will, if successful, be helpful to the coherentist theory of justification. Various impossibility results in the Bayesian coherentist literature are consequently taken to be prima facie detrimental to the coherentist theory of justification. These attempts to connect Bayesian coherentism to the coherentist/ foundationalist debate in classical epistemology rest upon a confusion between the justification of a proposition and the (...) credibility that a proposition has for some other proposition. Foundationalism requires a class of beliefs that have non- inferential justification, not beliefs that have credibility by themselves for others. Coherentists insist that beliefs can be justified only via inferential relations with others, but this does not mean that coherentists must deny that individual propositions can have credibility for other propositions. I analyze and respond to both Erik Olsson's and Michael Huemer's arguments concerning the alleged connection between the Bayesian coherentist project and the coherentist theory of justification. Finally, I argue that Bayesian coherentism as represented in the literature, so far from being a version of coherentism, is implicitly foundationalist because of its treatment of “witness reports”, especially the reports of memory and sensation, as given evidence. The impossibility results, based on the assumption of given reports, are therefore not targeted at classical coherentism in epistemology at all. (shrink)

Our claim in this paper is that not being identified as the data source might cause harm to a person or group. Therefore, in some cases the default of anonymisation should be replaced by a careful deliberation, together with research subjects, of how to handle the issues of identification and confidentiality. Our prime example in this article is community participatory research and similar endeavours on indigenous groups. The theme, content and aim of the research, and the question of how to (...) handle property rights and ownership of research results, as well as who should be in charge of the research process, including the process of creating anonymity, should all be answered, before anonymity is accepted. (shrink)

BackgroundIn the Canadian Alliance for Healthy Hearts and Minds (CAHHM) cohort, participants underwent magnetic resonance imaging (MRI) of the brain, heart, and abdomen, that generated incidental findings (IFs). The approach to managing these unexpected results remain a complex issue. Our objectives were to describe the CAHHM policy for the management of IFs, to understand the impact of disclosing IFs to healthy research participants, and to reflect on the ethical obligations of researchers in future MRI studies.MethodsBetween 2013 and 2019, 8252 participants (...) (mean age 58 ± 9 years, 54% women) were recruited with a follow-up questionnaire administered to 909 participants (40% response rate) at 1-year. The CAHHM policy followed a restricted approach, whereby routine feedback on IFs was not provided. Only IFs of severe structural abnormalities were reported.ResultsSevere structural abnormalities occurred in 8.3% (95% confidence interval 7.7–8.9%) of participants, with the highest proportions found in the brain (4.2%) and abdomen (3.1%). The majority of participants (97%) informed of an IF reported no change in quality of life, with 3% of participants reporting that the knowledge of an IF negatively impacted their quality of life. Furthermore, 50% reported increased stress in learning about an IF, and in 95%, the discovery of an IF did not adversely impact his/her life insurance policy. Most participants (90%) would enrol in the study again and perceived the MRI scan to be beneficial, regardless of whether they were informed of IFs. While the implications of a restricted approach to IF management was perceived to be mostly positive, a degree of diagnostic misconception was present amongst participants, indicating the importance of a more thorough consent process to support participant autonomy.ConclusionThe management of IFs from research MRI scans remain a challenging issue, as participants may experience stress and a reduced quality of life when IFs are disclosed. The restricted approach to IF management in CAHHM demonstrated a fair fulfillment of the overarching ethical principles of respect for autonomy, concern for wellbeing, and justice. The approach outlined in the CAHHM policy may serve as a framework for future research studies.Clinical trial registrationhttps://clinicaltrials.gov/ct2/show/nct02220582. (shrink)

Hegel’s philosophical system turns to a species of the laughable at three critical junctures of his dialectic: comedy appears both at the conclusion of classical art and of Hegel’s discussion of poetry, and romantic art ends with humor. But we misunderstand these transitional moments unless we recognize that Hegel did not use comedy and humor synonymously. Comedy refers to a dramatic genre with a 2000-year-old history; humor was a relatively recent aesthetic phenomenon that had become central to philosophizing about art (...) in Hegel’s generation. Hegel also differentiated between subjective humor, which he associated with the novelist Jean Paul’s eccentric excesses, and objective humor. Focusing on the surprising examples Hegel offers of objective humor— from epigrams to Persian poetry to the obscure novels of T.G. von Hippel—I argue that we better understand Hegel’s “end of art” thesis by tracing ways both comedy and humor can end. By understanding those endings, we also come closer to imagining how art can continue. (shrink)

I defend a sensitive neo-Moorean invariantism, an epistemological account with the following characteristic features: (a) it reserves a place for a sensitivity condition on knowledge, according to which, very roughly, S’s belief that p counts as knowledge only if S wouldn’t believe that p if p were false; (b) it maintains that the standards for knowledge are comparatively low; and (c) it maintains that the standards for knowledge are invariant (i.e., that they vary neither with the linguistic context of the (...) subject of knowledge nor with the linguistic context of the attributor of knowledge). I argue that this sort of account allows us to respond adequately to some difficult puzzles in epistemology, puzzles such as skeptical puzzles, as well as puzzles that inspire epistemological contextualism. I also maintain that by utilizing what Keith DeRose calls a warranted assertibility maneuver, sensitive neo-Moorean invariantism can account for our epistemic judgments in each of these puzzle cases. (shrink)

From 2009 to 2015, U.S. director, Quentin Tarantino, released three films that were notable for their focus on particular historical events, periods and individuals (Inglorious Basterds 2009; Django Unchained 2012; The Hateful Eight 2015). Together, these films offered a specifically “Tarantinian” rendering of history: rewriting, manipulating and, for some, unethically deploying history for aesthetic effect. With regard to Django Unchained, this article examines how Tarantino’s historical revisionism provides a valuable point of inquiry into the ways in which “history” is depicted (...) on-screen and, more importantly, how depictions of “the past” can prove useful for highlighting underlying contradictions, ambivalences and ambiguities in the “present”. Drawing upon Slavoj Žižek’s Lacanian approach to film analysis, it is argued that through a combination of fantasy, subversion and counterfactual possibility – most notable in the film’s final stand-off between its leading black characters – Tarantino is able to render the Real of U.S. slavery as an ahistorical antagonism. This antagonism highlights the ongoing trauma of these events in the present as well as the use of fantasy to explore their traumatic subject matter. Such historical fictions are not fixed to the past but, via an encounter with the Real, can be used to appraise the present. (shrink)

This article draws upon the work of Timothy Morton and Slavoj Žižek in order to critically examine how mountain bike trail builders orientated themselves within nature relations. Beginning with a discussion of the key ontological differences between Morton’s object-oriented ontology and Žižek’s blend of Hegelian-Lacanianism, we explore how Morton’s dark ecology and Žižek’s account of the radical contingency of nature, can offer parallel paths to achieving an ecological awareness that neither idealises nor mythologises nature, but instead, acknowledges its strange and (...) contingent form. Empirically, we support this theoretical approach in interviews with twenty mountain bike trail builders. These interviews depicted an approach to trail building that was ambivalently formed in/with the contingency of nature. In doing so, the trail builders acted with a sense of temporal awareness that accepted the radical openness of nature, presenting a ‘symbolic framework’ that was amiable to nature’s ambivalent, strange and contingent form. In conclusion, we argue that we should not lose sight of the ambivalences and strange surprises that emanate from our collective and unpredictable attempts to symbolize nature and that such knowledge can coincide with Morton’s ‘dark ecology’ – an ecological awareness that remains radically open to our ecological existence. (shrink)

According to a Moorean response to skepticism, the standards for knowledge are invariantly comparatively low, and we can know across contexts all that we ordinarily take ourselves to know. It is incumbent upon the Moorean to defend his position by explaining how, in contexts in which S seems to lack knowledge, S can nevertheless have knowledge. The explanation proposed here relies on a warranted-assertability maneuver: Because we are warranted in asserting that S doesn’t know that p, it can seem that (...) S does in fact lack that piece of knowledge. Moreover, this warranted-assertability maneuver is unique and better than similar maneuvers because it makes use of H. P. Grice’s general conversational rule of Quantity—“Do not make your contribution more informative than is required”—in explaining why we are warranted in asserting that S doesn’t know that p. (shrink)

In the Treatise, Book I, Part iv, Section 2, Hume seeks to explain what causes us to believe that objects continue to exist even when they are not perceived. He argues that we won't be able to prov...

Topics at a Poynter Institute privacy conference in December 1992 ranged from the role and obligations of the journalist to the rights of victims. Journalists' responsibility to fulfill a dual role of truthtelling and minimizing harm to vulnerable people in society framed the discussion. The public' s curiosity and media obsessions with information about victims of sex crimes are the first topics to be explored. Bob Steele of the Poynter Institute sets the stage for the delicate balance. Helen Benedict, author (...) of Virgin or Vamp: How the Press Covers Sex Crimes, suggests some reforms regarding this area of news. Patricia Bowman, a victim's advocate, talks about her experience as the victim of the media and of a celebrated sex crime case. Elinor Brecher of the Miami Herald discusses a particularly vexing assignment she recently faced, and Tom French of the St. Petersburg Times expresses concern for the subjects of sensitive personal stories and recommends trying to inform them about the story and help them cope with the intrusion into their private life. In separate articles, J. T. Johnson of Sartor Associates in San Francisco and Nora Paul of the Poynter Institute offer insights into the paradox of individual privacy and public right/desire to know, particularly as the issues arise in today's information society. Finally, Robert Ellis Smith, publisher of Privacy Journal, outlines ways media can approach privacy issues and still feel they are on safe ground; he recommends self-restraint in place of government restrictions. The general theme of the Poynter Conference is restraint and concern for others' responsible usage of information that has the possibility to harm others. (shrink)

So, C. I don’t know that T. Premises 1 and 2 are both plausible. However, C seems false—I do seem to know that there is a tree before me. AI presents a puzzle because its two plausible premises yield a conclusion whose negation is plausible. And no matter whether we accept or reject AI, we find that we must give up something plausible—either premise 1, premise 2, or the negation of C. But which of these should we give up? I (...) call this question the skeptical puzzle.1 Recently, Mark Heller2 has argued that we can solve the skeptical puzzle by giving up premise 2. I argue, however, that Heller does not adequately respond to an objection to his proposed solution. I go on to argue that we can solve the skeptical puzzle by giving up premise 1. (shrink)

The holographic principle was proposed by Nobel laureate Gerard ‘t Hooft in the 1990s and it has also been modeled by Leonard Susskind and Stephen Hawking. We’ve heard light mentioned with regard to the fundamental nature of reality for a long time; God said Let there be light, we are the light of the world, etc. But we haven’t investigated a possible role for the speed of light in our illnesses. This paper will do just that. The central premise is (...) that light’s “speed” is a reflection of the degree to which the observer is removed from its source. In its Platonic state, light’s speed is zero. It is light from which time, by degrees, emerges. The Big Bang can be envisioned as a sphere, the center of which is a point, Alpha. Via expansion, Alpha becomes a sphere, Omega, by degrees, where each degree is c. For any given Alpha, the circumference of a circle on the sphere, Omega, is a set of resonant points that represent the speed of light or “end of time.” Every radius—every line drawn from Alpha to Omega—is an arrow of time, a parallel universe. Alpha and Omega increase in tandem, maintaining the degree of separation required by special relativity, E=mc^2. The holographic sphere of points equidistant from the Big Bang on which we find ourselves is not the only sphere of points equidistant from the Big Bang. There are spheres that are smaller and larger than ours. Where an arrow of time intersects a sphere-brane of light’s speed will be treated here as a “2D hologram.” For an observer behind the hologram, reality will appear to be accelerating/expanding. For an observer in front of it, reality will appear to be decelerating/contracting. For an observer at the speed of light, time is no longer a variable. (shrink)

One of the many philosophical responses to scepticism is naturalism. It is explored how and to what extent it is successful in discussing these questions as they pertain external world scepticism. One interesting feature of naturalism is that it shares with scepticism the view that we lack proof and knowledge of an external world. The naturalist, however, unlike many sceptics and their more traditional disputants, doesn't think it matters. The first part of the paper contains a description of the naturalistic (...) response with emphasis on so-called frame-judgments. The second part is addressed to criticism of this response and replies to it. (shrink)

One of the many philosophical responses to scepticism is naturalism. It is explored how and to what extent it is successful in discussing these questions as they pertain external world scepticism. One interesting feature of naturalism is that it shares with scepticism the view that we lack proof and knowledge of an external world. The naturalist, however, unlike many sceptics and their more traditional disputants, doesn't think it matters. The first part of the paper contains a description of the naturalistic (...) response with emphasis on so-called frame-judgments. The second part is addressed to criticism of this response and replies to it. (shrink)

I agreed to come here today to speak on some such subject as "The Libertarian as Conservative." To me this is so obvious that I am hard put to find something to say to people who still think libertarianism has something to do with liberty. A libertarian is just a Republican who takes drugs. I'd have preferred a more controversial topic like "The Myth of the Penile Orgasm." But since my attendance here is subsidized by the esteemed distributor of a (...) veritable reference library on mayhem and dirty tricks , I can't just take the conch and go rogue. I will indeed mutilate the sacred cow which is libertarianism, as ordered, but I'll administer a few hard lefts to the right in my own way. And I don't mean the easy way. I could just point to the laissez faire Trilateralism of the Libertarian Party, then leave and go look for a party. It doesn't take long to say that if you fight fire with fire, you'll get burned. (shrink)

Women Activating Agency in Academia seeks to create and expand safe spaces for scholarly, professional and personal stories and assemblages of agency. It provides readers with the opportunity to connect with the strategies women are using to navigate academe and the core values, linked to trust, relationship, wellbeing and ethics of care, they live by. The collection offers the stories of women academics from around the globe and across disciplines and showcases their efforts to meaningfully listen and converse in order (...) to resist self-audit and diminished identities. Reflections come from a range of responsive, personal and aesthetic techniques, including writing groups, guided autobiography, auto-ethnography, collective activism and slow scholarship. Chapters engage with themes and ideas such as agency, neoliberalism, ontological security, androcentricity, identity and collegial support, which manifest in unique ways for female academics. The focus in this volume is what really matters to women in the academy, as they share their efforts to 'be' themselves in their work, to 'care for themselves and others' and to 'count what isn't counted'. It aims to prove how collaborative storytelling and discussion can empower female academics to preserve and achieve these ambitions. (shrink)

Sometimes ordinary disagreements become deep as a result of epistemic injustice. The paper explores a hitherto unnoticed connection between two phenomena that have received ample attention in recent social epistemology: deep disagreement and epistemic injustice. When epistemic injustice comes into play in a regular disagreement, this can lead to higher-order disagreement about what counts as evidence concerning the original disagreement, which deepens the disagreement. After considering a common definition of deep disagreement, it is proposed that the depth of disagreements is (...) best understood as a matter of degree. Then, a case study of real-life disagreement is introduced: the disagreement about whether racism is a significant issue in the Netherlands, illustrated by the tradition of ‘Black Pete’. It is argued that there is disagreement about what counts as evidence in the case study because of two forms of epistemic injustice: testimonial and hermeneutical injustice. Specifically, there is disagreement about epistemic principles concerning whether private first-personal experience of racism is a weighty source of evidence in this domain, whether victims of racism count as important testifiers in this domain, and how to assess testimony that is not intelligible to you because it employs concepts and terminology you are unfamiliar with. By dismissing the relevant testimony and epistemic resources, the disagreement boils down to disagreement on the level of epistemic principles concerning,, and. Introducinginjustice-based deep disagreementhighlights moral and political aspects of disagreements that might seem factual. (shrink)

Constructive Neutral Evolution is an evolutionary mechanism that can explain much molecular inter-dependence and organismal complexity without assuming positive selection favoring such dependency or complexity, either directly or as a byproduct of adaptation. It differs from but complements other non-selective explanations for complexity, such as genetic drift and the Zero Force Evolutionary Law, by being ratchet-like in character. With CNE, purifying selection maintains dependencies or complexities that were neutrally evolved. Preliminary treatments use it to explain specific genetic and molecular structures (...) or processes, such as retained gene duplications, the spliceosome, and RNA editing. Here we aim to expand the scope of such explanation beyond the molecular level, integrating CNE with Multi-Level Selection theory, and arguing that several popular higher-level selection scenarios are in fact instances of CNE. Suitably contextualized, CNE occurs at any level in the biological hierarchy at which natural selection as normally construed occurs. As examples, we focus on modularity in protein–protein interaction networks or “interactomes,” the origin of eukaryotic cells and the evolution of co-dependence in microbial communities—a variant of the “Black Queen Hypothesis” which we call the “Gray Queen Hypothesis”. (shrink)